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Discussion (1 Comments)Read Original on HackerNews

orangecatβ€’about 2 hours ago
Good. If https://www.astralcodexten.com/p/in-defense-of-the-amyloid-h... is correct, the reason existing anti-amyloid drugs don't work well is amyloid leads to tau which leads to neurodegeneration, so by the time somebody is impaired by Alzheimer's they already have too much tau and reducing amyloid won't help much.