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He was an early participant in one of these psychedelic studies a few years ago. After the first treatment, he said he couldn't really tell if it had any effect. But six months later, he was totally changed - able to function almost normally.
We should exercise our usual amount of skepticism about miracle treatments, but my hope is that his experience can be replicated.
(I’ll try to search for it when I have free time)
Psychedelic trips are taxing on the body and I think I agree with the hypothesis nutrients are underestimated in supporting a healthy mind in these states, from personal experience.
Charitably, you could argue a functional society involves some amount of indoctrination into a set of shared beliefs and a large percentage of people losing that indoctrination would destroy society. Could the US function if everyone was a pacifist, anti-capitalist, hippie? I think that was and still is the primary concern.
I'm not saying that everyone should go do LSD and I don't know the details or stories of the people you saw. Like I said, I understand the perspective of people who feel responsible for maintaining a societal order. I'm just trying to point out how relative all of this is to societal frameworks.
Way to generalise. I also know people who drank water, went to sleep and never woke up.
Ego dissolution is dosage dependent and you don't need to reach that point to get positive benefits.
Also, many people do psychdelics that probably shouldn't.
If you want to specify LSD, you should do that, not "psychedelics." There are many, many psychedelics. They have sometimes radical differences. You cannot generalize that word into "many people never make it back." That is flat-out wrong, not to mention harmful.
but anyone i have met that did Psychedelics more than a few times, permanently changed their brain chemistry in a way that was obvious. clearly they are doing some kind of unraveling that doesnt fully bounce back
Psychedelics does however have longterm behavioural effects that are statistically significant and to some extent observable.
Using a definition of brain chemistry that defines brain chemistry at an atomic level you may assert that a change in behavioural patterns reflect a change in brain chemistry. But with such a definition anything that a person experiences does that.
ive barely taken them, but i watched many people change over years of use.
I've watched hundreds of people take them in great containers with great support. It's never a good idea to make big changes right away, but we take small steps to adjust our lives so we can actually be happy. Yes, even if that is less "productive". Why do we do the things we do anyways?
They might say the same thing about your lifestyle. The "reward structure of society" is highly abstract these days, arguably disconnected from "real life". You could say monks are disconnected from "real life."
This is a weird take, I think.
Psychedelics are likely to be a good option for some patients, it's good to have another tool in the armamentarium, but the idea that they're a revolution in psychiatry is simply no longer credible.
https://pubmed.ncbi.nlm.nih.gov/39627679/
Disclosure: I have participated in a clinical trial of psilocybin for treatment-resistant depression and did not see any meaningful benefit.
In German it's Droge and Medikament
Cleave: To split apart ('cleave the wood') or to adhere closely ('cleave to one's principles')
Sanction: To give official permission/approval or to impose a penalty/ban
Oversight: Watchful supervision or an unintentional mistake/omission
Dust: To remove fine particles ('dust the shelf') or to sprinkle them on ('dust the cake with sugar')
Bolt: To secure firmly in place or to run away suddenly
Clip: To fasten together ('clip the papers') or to cut off ('clip the coupon')
Fast: Moving quickly or fixed firmly in place ('stuck fast')
Left: Departed (verb) or remaining (adjective)
Screen: To display/show ('screen a movie') or to hide/conceal
Weather: To withstand or endure ('weather the storm') or to wear away/deteriorate over time
Peruse: To read carefully and thoroughly or to skim casually
Trim: To decorate/adorn ('trim the tree') or to cut away excess ('trim the hedges')
Rent: To pay for the use of something or to receive payment for allowing someone to use something
Table: In British English, to propose for discussion; in American English, to postpone or remove from discussion
I've partaken of 'shrooms a number of times: Fun times. I've even grown them (protip - not worth the trouble. It's amazing how something that grows in literal shit is suddenly the most fragile process imaginable when you try your PFTek method, and contamination will always be ruining your process). But people keep trying to make psilocybin a magic solution, and the studies have been extremely weak if not contradictory, and these stories always lean on worthless anecdotes.
But you're also totally right - my story is just an anecdote, and these sort of headlines that used to have cannabis as a miracle cure for all types of things seem to have been replaced with headlines about psilocybin (or occasionally, ketamine) curing everything instead. I totally get the skepticism, but I'm a believer that we might be onto something w/r/t depression or other things that are treatable via CBT at least - the article mentioned "combined with talk therapy" ... not sure what therapy method was used alongside the psilocybin.
The drug won't magically give you the answer but you may reach some more profound general breakthroughs regarding your own behavior, patterns you fall into unconsciously, etc.
Similar to how addiction and associated behaviors are really only resolved when the person addicted decides to make the change, you can use these to influence into a similar state.
Psilocybin opens up new pathways to treating anorexia