Human brain changes after first psilocybin use

takyamoto•about 3 hours ago

Microdosing can literally be a lifesaver if you have chronic depression or PTSD. It's been widely documented and there's tons of companies working on this specifically as a new form of treatement.

unanonymousanon•about 2 hours ago

What do you consider a micro dose? The article states: “All effects are exclusive to 25 mg psilocybin; no effects occur with a 1 mg psilocybin placebo”

genewitch•36 minutes ago

they sell psilocybin gummies, ranging from weak to 4.5g per. The ones i've tried were "3 is a normal dose, 6 is space jam, 1 is a nice afternoon off." I took one, and it did make everything a little brighter, birds sweeter sounding, and everything seemed a little bit better for a while. But i don't trust the manufacturers, so i only tried 1 pack over a couple of weeks.

anyhow 1-25mg is a pretty small does if 5g is considered a hero dose per siblings.

I haven't tried tons of nootropics like this, but i have tried Kanna, Kratom, psilocybin, CBD, delta-9 THC, THC-P, hydrogenated THC, salvia, and i'm probably forgetting a lot. Belladonna, that's one i tried before, for example. just came to me.

I don't do "hard" drugs, though, never have, no desire to. I do like plants, though.

nurettin•12 minutes ago

> took one, and it did make everything a little brighter, birds sweeter sounding, and everything seemed a little bit better for a while.

Used to work at a dreary sweatshop where breaks amounted to smoking outside while staring at eachother, they used biometrics and software to track your KPIs , you'd get diarrhea from workplace food and departments had various beefs with each other.

Switched jobs to an international car manufacturer where people would greet eachother, drop their guards and have fun working together.

I got this exact feeling! The sky was more blue, flowers were more colorful, birds more chirpy, halls brighter and people smiled. Lasted for five months.

harimau777•about 1 hour ago

5 grams is considered a heroic dose (e.g. the dose where you are likely to experience things like ego death).

Around 2 grams is considered a "museum dose" or "social dose" (e.g. it's enough to change your perceptions but not so much that you are unable to operate).

So 25 mg is a fairly low dose while 1 mg is very low.

nolroz•15 minutes ago

I looked at the study and it appears that it's 25 mg of synthetic psilocybin. So assuming that's equivalent to 100% psilocybin and mushrooms average around .6% dry then it would be like 4g dry mushrooms.

polishdude20•16 minutes ago

5 grams of mushrooms is not the same as 5 grams of psilocybin. When taking about mg, I think they mean psilocybin. When talking about grams, it's mushrooms

xattt•about 2 hours ago

> Microdosing can literally be a lifesaver

> All effects are exclusive to 25 mg psilocybin; no effects occur with a 1 mg psilocybin placebo.

harimau777•about 2 hours ago

Have they figured out a way around the interactions with SSRIs yet?

evanjrowley•about 3 hours ago

They feed us poison, so we buy their "cures", while they suppress our medicine.

Human brain changes after first psilocybin use

⚡ Community Insights

Discussion (10 Comments)Read Original on HackerNews